RESOURCES

Technical guides for supplement manufacturers

Practical guidance on equipment, ingredients, packaging and regulatory compliance for EU supplement production.

Production Equipment

CE Marking for Supplement Equipment: What Manufacturers Need to Know

Understanding what CE Declaration of Conformity covers, what auditors expect to see on a site visit, and how to verify that a machine you're sourcing actually qualifies.

Capsule Shells

Choosing Between HPMC and Gelatin Capsule Shells

A technical comparison of HPMC and gelatin shells covering dissolution profiles, moisture sensitivity, fill compatibility, and cost implications at volume.

Raw Ingredients

COA Review Checklist for Supplement Ingredients

The minimum a quality manager should verify on a Certificate of Analysis before releasing a raw material batch to production.

Facility Components

GMP Facility Layout: Key Zones and Flow Requirements

How to design material and personnel flows in a supplement manufacturing facility to satisfy EU GMP Annex 1 and 2 requirements.

Packaging

Blister Packaging Formats: PVC, PVDC and Aluminium

When each blister substrate is appropriate, how barrier properties affect shelf life, and tooling compatibility considerations.

Regulatory

EU Supplement Ingredient Restrictions: What Changed in 2024

A summary of Novel Food approvals, maximum level updates and new documentation requirements that came into effect across the EU supplement market.